amylin/GLP-1 combinationGLP-1 Agonists

CagriSema

A combination of cagrilintide (long-acting amylin analog) and semaglutide. Phase 3 REDEFINE-1 showed 20.4% weight loss. NDA submitted December 2025. Combines two complementary appetite-regulating pathways.

weight-lossappetite-suppressioncombination-therapyexperimental
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Summary

A combination of cagrilintide (long-acting amylin analog) and semaglutide. Phase 3 REDEFINE-1 showed 20.4% weight loss. NDA submitted December 2025. Combines two complementary appetite-regulating path…