cyclic peptideTherapeutic Peptides
Cyclosporine A
A cyclic undecapeptide from the fungus Tolypocladium inflatum. FDA-approved immunosuppressant for organ transplantation, autoimmune diseases, and dry eye. Inhibits calcineurin/NFAT pathway. One of the most commercially successful peptide drugs.
immunosuppressionorgan-transplantautoimmunecalcineurin-inhibitorFDA-approved
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Summary
A cyclic undecapeptide from the fungus Tolypocladium inflatum. FDA-approved immunosuppressant for organ transplantation, autoimmune diseases, and dry eye. Inhibits calcineurin/NFAT pathway. One of the…