GIP antagonist/GLP-1 agonistGLP-1 Agonists
MariTide (Maridebart Cafraglutide)
A once-monthly injectable antibody-peptide conjugate from Amgen combining GIP receptor antagonism with GLP-1 agonism. Phase 2 showed 12-16% weight loss. Unique monthly dosing could improve adherence.
weight-losslong-actingmonthly-dosingexperimental
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Summary
A once-monthly injectable antibody-peptide conjugate from Amgen combining GIP receptor antagonism with GLP-1 agonism. Phase 2 showed 12-16% weight loss. Unique monthly dosing could improve adherence.