complement inhibitor peptideTherapeutic Peptides
Pegcetacoplan (Empaveli)
A PEGylated cyclic peptide that binds complement C3. FDA-approved for paroxysmal nocturnal hemoglobinuria (PNH) and geographic atrophy. First targeted C3 inhibitor, blocking complement at its central node.
complement-inhibitionPNH-treatmentgeographic-atrophyFDA-approved
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Summary
A PEGylated cyclic peptide that binds complement C3. FDA-approved for paroxysmal nocturnal hemoglobinuria (PNH) and geographic atrophy. First targeted C3 inhibitor, blocking complement at its central …